When osseointegration was first introduced by Brånemark as a therapy for the replacement of the natural dentition, it was accepted as an appropriate and predictable solution for young and middle-aged edentulous patients. No one anticipated the positive results and high level of acceptability that this therapy would bring about. The decision regarding whether to save a tooth or insert an implant is one that the implant clinician makes based on previous experience, recently approved therapeutics, and the best interests of the patient. This high-quality and timely publication will serve to enhance the armamentarium of implant clinicians in this regard. The editors have engaged leading thinkers in surgery and prosthetics to share their methods, ranging from prevention to regeneration. The text provides contemporary information for achieving constructive endpoint goals and for managing solutions to peri-implantitis and should have a place in every dental library.



Dr. Alberto Monje obtained the certificate and Masters in Periodontology from the University of Michigan, Department of Periodontics and Oral Medicine. Since them, he is certified by the American Board of Periodontics. He was the recipient of the ITI Scholarship for 2016-2017 at the University of Bern (Switzerland). Dr. Alberto Monje is PhD in the field of alveolar bone architecture granted by the University of Granada (Spain). He holds a private practice exclusive in Periodontics and Implant Dentistry (CICOM Periodoncia). He is Adjunct Professor at the Department of Periodontics of the Universitat Internacional de Catalunya (Barcelona, Spain), and Assistant Clinical Professor at the Department of Periodontics and Oral Medicine at the University of Michigan (Ann Arbor, USA). Dr. Monje is Visiting Professor at the Department of Periodontology of the University of Bern (Switzerland).



Hom-Lay Wang, DDS., MSD., Ph D, Professor and Director of Graduate Periodontics at the University of Michigan.He has co-editor two textbooks, published more than 50 book chapters/invited reviews and more than 750 peer-reviewed scientific articles. Dr. Wang serves as a Co-Editor-in-Chief for Clinical Implant Dentistry and Related Research, an Associate Editor for The IJOMI and IJOI.Dr. Wang is the recipient of many awards/honors including AAP Outstanding Educator Award (2017), AAP Distinguished Scientist Award (2017),AAP Master Clinician Award (2019), AAP Distinguished Service Award (2021), and AAP Clinical Research Award (2021).



Contents

Chapter 01. Unfolding the Initiation and Progression of Peri-Implantitis: The Scope of the Problem

Chapter 02. Diagnosis and Monitoring of Peri-Implant Conditions

Chapter 03. In Vitro Diagnostics in Monitoring Peri-Implant Conditions

Chapter 04. Morphologic and Phenotypical Characteristics of Peri-Implantitis

Chapter 05. Critical Peri-Implant Soft Tissue Dimensions in Health and Disease

Chapter 06. Critical Peri-Implant Hard Tissue Dimensions in Health and Disease

Chapter 07. Local Confounders of Peri-Implantitis: Predisposing, Precipitating, and Accelerating Factors

Chapter 08. Systemic Confounders and Deleterious Habits Associated with Peri-Implantitis

Chapter 09. Genetic and Epigenetic Susceptibility of Peri-Implantitis

Chapter 10. Primary Prevention of Peri-Implantitis: Peri-Implant Supportive Maintenance Therapy

Chapter 11. Secondary Prevention of Peri-Implantitis: Management of Peri-Implant Mucositis

Chapter 12. Management of Peri-Implantitis. Part 1: Lessons Learned from the Treatment of Periodontitis

Chapter 13. Management of Peri-Implantitis. Part 2: A Simplified Decision-Making Process

Chapter 14. Non-Surgical Treatment for Peri-Implantitis

Chapter 15. Pharmacologic Adjuncts for the Management of Peri-Implantitis

Chapter 16. Strategies for Implant Surface Detoxification

Chapter 17. Surgical Resective Therapy of Peri-Implant Defects: When and How?

Chapter 18. Part I. Reconstructive Therapy for the Management of Peri-Implantitis

Chapter 18. Part II. The EP-DDS Protocol for Reconstructive Therapy. A New Perspective in the Management of Peri-Implantitis

Chapter 19. Soft Tissue Conditioning for the Prevention and Management of Peri-Implantitis

Chapter 20. The Use of Biologic Agents in Peri-Implantitis Therapy: Rationale and Efficacy

Chapter 21. Management of Peri-Implant Soft Tissue Dehiscences in the Esthetic Zone

Chapter 22. Future Perspectives in the Understanding of Peri-Implantitis