Vaping and the reemergence of adolescent nicotine use is one of the more pressing US public health challenges of the past decade. This book compiles, in one accessible resource, a menu of intervention options and strategies for adults looking to promote teens' optimal health-related decision making. Written for clinicians, researchers, and educators, while also remaining accessible to concerned families, this volume integrates the latest scientific findings, developmental perspectives, and clinical recommendations focused on preventing and treating teen vaping. By appreciating the broad biopsychosocial context in which vaping behaviors arise and persist, this guide advocates for the tailoring of interventions to individual needs and preferences, highlighting youth-oriented practical tools for vaping education, prevention, and treatment. A primary goal is to inspire collaborative, multilevel efforts to protect the health and well-being of the next generation. Teen vaping is a preventable and treatable health challenge when addressed with urgency, scientific evidence, and empathy.